Canine atopic dermatitis
Definition
Atopic dermatitis is an inhirited tendency to respond to environmental allergens by developing a type 1 hypersensitivity
Etiology
Canine atopic dermatitis results from a genetic predisposition to become sensitized to environmental allergens. Although the route of allergen access is still controversial, inhalation and percutaneus absorption of these allergens seem weekly
Pathophysiology
The pathophysiology is still unclear in animals. In humans atopic dermatitis is associated with increased activation of T lymphocytes, defective cell mediated immunity, hyper stimulatory langerhans cells and overproduction of B cell IgE
Clinical presentation
Atopic dermatitis usually affects young adult dogs (onset at 1—3 years old) with a seasonal purity. It is important to discern the presence, intensity and frequency of itch; flea eradication programs; and previous treatment and effect. Pruritus should be evident and effect one or more of the following areas: face extensor and flexor skin surfaces, axilla, pinna and groin
Differential diagnosis
Sarcoptic mange, Cheyletiellosis, pediculosis, contact allergic dermatitis, food hypersensitivity, and flea bite hypersensitivity, pelodera strongyloides dermatitis, malassezia dermatitis, superficial pyoderma, xerosis.
Diagnosis
Diagnosis of atopic dermatitis is based on compatible historical and clinical information, as well as ruling out other causes of purities. Secondary diseases may also contribute to the puritan threshold in the atopic patient and these can be recurrent problems which must be continually addressed; otitis externa or otitis media, superficial pyoderma, acute moist dermatitis, keratinizations disorders, malassezia dermatitis, flea bite hypersensitivity (common in dogs with atopic dermatitis), acral lick dermatitis and fibropruritic nodules
Management
When allergen avoidance is not possible, hypo sensitizations is the treatment of choice for animals with a prolonged allergy seasons. Hypo sensitization based on in vitro or in vivo allergy testing is affective in decreasing purities or reducing the need for other medications in 60-80% of dogs. The success of hypo sensitizations may note for 3-12 months.
Symptomatic therapy includes the use of antihistamines and essensitial fatty acids, topical antipruritic therapy, oral alternate day corticosteroids and avoidance (if possible), as well as managing secondary problems.
( source vet-zone )
Atopic dermatitis is an inhirited tendency to respond to environmental allergens by developing a type 1 hypersensitivity
Etiology
Canine atopic dermatitis results from a genetic predisposition to become sensitized to environmental allergens. Although the route of allergen access is still controversial, inhalation and percutaneus absorption of these allergens seem weekly
Pathophysiology
The pathophysiology is still unclear in animals. In humans atopic dermatitis is associated with increased activation of T lymphocytes, defective cell mediated immunity, hyper stimulatory langerhans cells and overproduction of B cell IgE
Clinical presentation
Atopic dermatitis usually affects young adult dogs (onset at 1—3 years old) with a seasonal purity. It is important to discern the presence, intensity and frequency of itch; flea eradication programs; and previous treatment and effect. Pruritus should be evident and effect one or more of the following areas: face extensor and flexor skin surfaces, axilla, pinna and groin
Differential diagnosis
Sarcoptic mange, Cheyletiellosis, pediculosis, contact allergic dermatitis, food hypersensitivity, and flea bite hypersensitivity, pelodera strongyloides dermatitis, malassezia dermatitis, superficial pyoderma, xerosis.
Diagnosis
Diagnosis of atopic dermatitis is based on compatible historical and clinical information, as well as ruling out other causes of purities. Secondary diseases may also contribute to the puritan threshold in the atopic patient and these can be recurrent problems which must be continually addressed; otitis externa or otitis media, superficial pyoderma, acute moist dermatitis, keratinizations disorders, malassezia dermatitis, flea bite hypersensitivity (common in dogs with atopic dermatitis), acral lick dermatitis and fibropruritic nodules
Management
When allergen avoidance is not possible, hypo sensitizations is the treatment of choice for animals with a prolonged allergy seasons. Hypo sensitization based on in vitro or in vivo allergy testing is affective in decreasing purities or reducing the need for other medications in 60-80% of dogs. The success of hypo sensitizations may note for 3-12 months.
Symptomatic therapy includes the use of antihistamines and essensitial fatty acids, topical antipruritic therapy, oral alternate day corticosteroids and avoidance (if possible), as well as managing secondary problems.
( source vet-zone )
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